in my opinion the best runes called champion runes, can be collected in PVP, only.
With a lot of luck and a huge amount of materials and money you are able to craft/get similar runes, but I have been predominantely unlucky...
For myself I can state, that I don't like it to be forced doing a lot of PVP, if I would like to collect such fine runes.
It would be nice (especially for the players disliking PVP), if the champion runes have a counterpart to be found for huge efforts in PVE and Guild Games.
Possibly make them all craftable, equivalent as suggestet here: